| Malabsorption syndrome associated with ulceration of the stomach and small bowel caused by chronic intestinal ischemia in a patient with hyperhomocysteinemia. | |
| | |
MedLine Citation:
|
PMID: 9179139 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We describe a 39-year-old woman with an 8-month history of abdominal pain, diarrhea, and weight loss. Clinical and laboratory evaluation indicated the presence of a malabsorption syndrome. Endoscopy revealed multiple gastric ulcerations and an abnormal "picture" of the duodenal mucosa. At duodenal biopsy, necrosis confined to the distal parts of the enteric villi and a polymorphonuclear leukocyte response were found. Further evaluation revealed intestinal ischemia as a result of mesenteric atherosclerosis. After a revascularization procedure was performed, the symptoms disappeared. The macroscopic and microscopic picture of the bowel normalized. In our search for risk factors of atherosclerosis, we found a substantially increased basal plasma homocysteine concentration. This case suggests that hyperhomocysteinemia may have a causal role in the development of symptomatic, premature atherosclerosis of the mesenteric circulation. |
| | |
Authors:
|
R C Bakker; D P Brandjes; P Snel; J A Lawson; J Lindeman; D Batchelor |
Related Documents
:
|
6538959 - Primary abdominal pregnancy in the spleen: a case report. 2094649 - Anthropometry of seated women during pregnancy: defining a fetal region for crash prote... 115269 - Incidental detection of pericardial effusions on abdominal ultrasound studies. 17331509 - Peri-implantation pelvic inflammatory disease with normal pregnancy outcome. 9076919 - Postpartum mummification of a co-twin fetus in a cameroon dwarf goat doe. 12521699 - Musculo-skeletal problems associated with pregnancy in women with osteogenesis imperfecta. 12287149 - Coping with an unplanned pregnancy. 11400769 - Prenatal ultrasound diagnosis in thailand. 12078969 - Benign mucinous cystadenoma with stromal luteinization during pregnancy: a hormonally r... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Mayo Clinic proceedings. Mayo Clinic Volume: 72 ISSN: 0025-6196 ISO Abbreviation: Mayo Clin. Proc. Publication Date: 1997 Jun |
Date Detail:
|
Created Date: 1997-07-16 Completed Date: 1997-07-16 Revised Date: 2007-10-29 |
Medline Journal Info:
|
Nlm Unique ID: 0405543 Medline TA: Mayo Clin Proc Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 546-50 Citation Subset: AIM; IM |
Affiliation:
|
Department of Gastroenterology, Slotervaart Hospital, Amsterdam, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Chronic Disease Duodenal Ulcer / complications*, pathology Female Homocysteine / blood* Humans Intestines / blood supply*, pathology Ischemia / complications*, pathology Malabsorption Syndromes / etiology*, pathology Splanchnic Circulation Stomach Ulcer / complications*, pathology |
| Chemical | |
Reg. No./Substance:
|
454-28-4/Homocysteine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Trigeminal trophic syndrome.
Next Document: Surgical treatment of obesity: who is an appropriate candidate?