Document Detail

Making sense of cell lineage.
MedLine Citation:
PMID:  8087539     Owner:  NLM     Status:  MEDLINE    
In this article I describe what I see as the sources of confusion in the description and interpretation of cell lineage data. I concentrate on lineage in the nervous system, since that is my interest, but most of the arguments are broadly applicable. Since there are these differences between workers in the field, all will not agree with my perspective, but perhaps a consensus can evolve from the discussion. I see the problem as having two facets: First, there is a confusion surrounding terminology, which leads to too many different types of studies to be considered as studies of cell lineage; and second, there is some confusion about what can validly be concluded from a study of cell lineage.
J Price
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Perspectives on developmental neurobiology     Volume:  1     ISSN:  1064-0517     ISO Abbreviation:  Perspect Dev Neurobiol     Publication Date:  1993  
Date Detail:
Created Date:  1994-10-19     Completed Date:  1994-10-19     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9417971     Medline TA:  Perspect Dev Neurobiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  139-48     Citation Subset:  IM    
National Institute for Medical Research, London, UK.
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MeSH Terms
Cell Differentiation*
Chick Embryo
DNA, Viral / analysis
Drosophila melanogaster / genetics,  metabolism
Embryo, Mammalian / cytology
Embryo, Nonmammalian
Embryonic and Fetal Development
Nervous System / cytology,  embryology
Proviruses / genetics
Retroviridae / genetics
Stem Cells / cytology,  microbiology
Virus Integration
Reg. No./Substance:
0/DNA, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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