Document Detail


Making a rash diagnosis: amoxicillin therapy in infectious mononucleosis.
MedLine Citation:
PMID:  2140384     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ampicillin analog, amoxicillin, can potentially produce the same hypersensitivity reaction as the ampicillin. The case of a patient treated with amoxicillin for a sore throat, who later presented with a rash, is reviewed. Infectious mononucleosis was considered and then supported by a positive mono spot. It would appear therefore that amoxicillin can produce the same hypersensitivity reaction as ampicillin in the setting of acute infectious mononucleosis. The clinical decision to use antibiotics in acute pharyngitis is complicated by the identical presentation of both viral and bacterial illnesses. If empiric therapy is elected, the incidence of hypersensitivity reaction is less common with penicillin or tetracycline compared to ampicillin or its analog, amoxicillin.
Authors:
M E Pauszek
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Indiana medicine : the journal of the Indiana State Medical Association     Volume:  83     ISSN:  0746-8288     ISO Abbreviation:  Indiana Med     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-06-25     Completed Date:  1990-06-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8401780     Medline TA:  Indiana Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  330-1     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Amoxicillin / adverse effects*
Drug Eruptions / etiology*
Drug Hypersensitivity / etiology*
Female
Humans
Infectious Mononucleosis / drug therapy*
Pharyngitis / drug therapy
Chemical
Reg. No./Substance:
26787-78-0/Amoxicillin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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