Document Detail


Making preventive medicine more personalized: implications for exercise-related research.
MedLine Citation:
PMID:  22588227     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: This commentary offers a discussion of the need to consider behavioral interventions such as physical exercise as integral components of personalized medicine.
METHODS: We discuss the concept of personalized medicine and review existing evidence of variability in response to exercise training.
RESULTS: We argue that increased understanding is needed regarding sources of variability in exercise responsiveness, and that such understanding should lead to more tailored, often multimodal interventions.
CONCLUSION: Studies of personalized medicine to date have primarily investigated heterogeneity in drug responsiveness; we believe it is time to begin considering preventive strategies such as exercise within a broader scope of personalized care.
Authors:
Thomas W Buford; Marco Pahor
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2012-05-14
Journal Detail:
Title:  Preventive medicine     Volume:  55     ISSN:  1096-0260     ISO Abbreviation:  Prev Med     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-06-18     Completed Date:  2012-11-13     Revised Date:  2014-07-10    
Medline Journal Info:
Nlm Unique ID:  0322116     Medline TA:  Prev Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  34-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Community-Institutional Relations
Exercise* / psychology
Genomics
Guideline Adherence
Health Behavior*
Health Policy
Health Promotion / methods*
Health Services Research
Humans
Individualized Medicine / utilization*
Organizational Innovation
Outcome and Process Assessment (Health Care)
Pharmacogenetics
Physician-Patient Relations
Preventive Medicine / methods*,  trends
United States
Grant Support
ID/Acronym/Agency:
1KL2RR029888/RR/NCRR NIH HHS; 1P30AG028740/AG/NIA NIH HHS; KL2 RR029888/RR/NCRR NIH HHS; P30 AG028740/AG/NIA NIH HHS
Comments/Corrections
Erratum In:
Prev Med. 2013 Jan;56(1):94

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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