Document Detail


Major histocompatibility complex monomorphism and low levels of DNA fingerprinting variability in a reintroduced and rapidly expanding population of beavers.
MedLine Citation:
PMID:  8367476     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Loss of genetic variation due to population bottlenecks may be a severe threat for the survival of endangered species. Assessment and maintenance of genetic variability are thus crucial for conservation programs related to endangered populations. Scandinavian beavers went through an extensive bottleneck during the last century due to overhunting. In Sweden the species became extirpated but in Norway extinction was avoided by legal protection. Following reintroductions of small numbers of remaining Norwegian animals in 1922-1939, the Swedish population has increased tremendously, now harboring 100,000 animals. We show here that this viable population of beavers possesses extremely low levels of genetic variability at DNA fingerprinting loci and monomorphism at major histocompatibility complex (MHC) class I and class II loci. A similar pattern was also evident among Norwegian beavers but low levels of genetic variability were not a characteristic of the species since Russian conspecifics displayed substantial DNA fingerprinting polymorphism. However, the Russian animals were monomorphic at MHC loci, indicating that the European beaver is exceptional in its low level of MHC variability. The results demonstrate that a conservation program can be successful despite low levels of genetic variation in the founder population.
Authors:
H Ellegren; G Hartman; M Johansson; L Andersson
Related Documents :
23021696 - Single-nucleotide polymorphisms in genes involved in placental function and unexplained...
11403866 - The genetics of species differences.
25401986 - Comparing partial least square approaches in a gene- or region-based association study ...
21235546 - Genetic structure and phylogeography of two freshwater fishes, rhadinocentrus ornatus a...
22022476 - Common genetic variants are associated with accelerated bone mineral density loss after...
11092196 - Update on the genetics of the idiopathic inflammatory myopathies.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Proceedings of the National Academy of Sciences of the United States of America     Volume:  90     ISSN:  0027-8424     ISO Abbreviation:  Proc. Natl. Acad. Sci. U.S.A.     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1993-10-05     Completed Date:  1993-10-05     Revised Date:  2010-09-10    
Medline Journal Info:
Nlm Unique ID:  7505876     Medline TA:  Proc Natl Acad Sci U S A     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  8150-3     Citation Subset:  IM    
Affiliation:
Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
DNA / genetics*
DNA Probes
Genetic Variation*
Genetics, Population*
Major Histocompatibility Complex / genetics*
Norway
Restriction Mapping
Rodentia / genetics*
Russia
Sweden
Chemical
Reg. No./Substance:
0/DNA Probes; 9007-49-2/DNA
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A transcription inhibitor specific for unwound DNA in RNA polymerase-promoter open complexes.
Next Document:  Glyceraldehyde-3-phosphate dehydrogenase on the surface of group A streptococci is also an ADP-ribos...