Document Detail

Maintenance of viable arterial allografts by cryopreservation.
MedLine Citation:
PMID:  635775     Owner:  NLM     Status:  MEDLINE    
An experimental study, designed to investigate the feasibility of maintaining fresh, viable arterial allografts by cryopreservation, is presented. Cryopreserved femoral arterial allografts were shown to be equal in patency rate when compared with fresh controls. The cryopreserved allografts were shown to be superior to fresh allografts in the parameters of intimal integrity, absence of host rejection, and reduced surface thrombogenicity. This experimental study supports the thesis that cryopreservation in liquid nitrogen, utilizing 15% dimethyl sulfoxide (DMSO) and methylprednisolone as a cryoprotectant solution, is an excellent method of preserving and storing fresh allograft arteries for use as a small vessel replacement.
C H Boren; A J Roon; W S Moore
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Surgery     Volume:  83     ISSN:  0039-6060     ISO Abbreviation:  Surgery     Publication Date:  1978 Apr 
Date Detail:
Created Date:  1978-05-08     Completed Date:  1978-05-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0417347     Medline TA:  Surgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  382-91     Citation Subset:  AIM; IM    
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MeSH Terms
Arteritis / etiology,  pathology
Blood Vessel Prosthesis
Carotid Arteries / cytology,  pathology,  transplantation*
Femoral Artery / cytology,  pathology,  transplantation*
Postoperative Complications
Thrombosis / etiology
Tissue Preservation*
Transplantation, Homologous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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