Document Detail


Maintenance intravenous iron therapy in hepmodialysis patients receiving recombinant human erythropoientin.
MedLine Citation:
PMID:  18212409     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Iron Supplementation is crucial in raising hematocrit as well as dosage saving for recombinant human erythropoietin therapy (rHuEPO) in maintenance hemodialysis patients. Intravenous iron has proved to be both safe and efficacious in this patient's population. However, the exact iron requirement has not been worked our. In this study we found that 1000 mg of element iron (given as iron saccharate) per moth was effective in maintaining hematocrit and hemoglobin at 33% and 110 gm/L respectively, and reducing the erythropoietin (EPO) dosage by about 20% in maintenance hemodialysis patients who were iron-replete. The serum ferritin increased from 219+/-144 to 320+/-234 microg/L (P< 0.05). There were no major side effects and patients tolerated the monthly iron therapy well. Our study suggests that intravenous iron saccharate (100 mg/month) is effective and safe in patients on maintenance hemodialysis receiving RHUEPO.
Authors:
S A Romeh; S Huraib; N Murray; D Tanimu; A Flaiw; A Iqbal; G Al Ghamdi; K Quadri
Related Documents :
11347329 - Epoetin-beta (recormon-roche) in the treatment of renal anemia in patients with chronic...
2585159 - Pica: its frequency and significance in patients with iron-deficiency anemia due to chr...
7387309 - Primary hemochromatosis with hereditary spherocytosis.
18499399 - Comparison of ferrous sulfate and ferrous glycinate chelate for the treatment of iron d...
9401499 - Ticlopidine-induced aplastic anemia: report of three chinese patients and review of the...
3385529 - Diaphyseal dysplasia associated with anemia.
16830639 - Clinical and histologic variations among thirty patients with lucio's phenomenon and pu...
16088649 - Ocular manifestations of sarcoidosis.
23760319 - Photosensitive spongiotic/lichenoid eruption of micropapules and plaques: a morphologic...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia     Volume:  10     ISSN:  1319-2442     ISO Abbreviation:  Saudi J Kidney Dis Transpl     Publication Date:    1999 Jan-Mar
Date Detail:
Created Date:  2008-01-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9436968     Medline TA:  Saudi J Kidney Dis Transpl     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  21-5     Citation Subset:  -    
Affiliation:
Department of Nephroogy, King Fahad National Guard Hospital, Riyadh, Saudi Arabia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Influence of melatonin and its precursor L-tryptophan on Th1 dependent contact hypersensitivity.
Next Document:  Cyclosporine neoral: a local experience.