Document Detail


Maintenance electroconvulsive therapy for Parkinson's disease.
MedLine Citation:
PMID:  9437571     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In two patients with severe Parkinson's disease (PD) whose response to levodopa had decreased, the parkinsonian motor symptoms responded to acute and maintenance unilateral electroconvulsive therapy (ECT). Case 1 relapsed while taking antiparkinsonian medication 2 and 3 months after two brief courses of ECT. After another relapse, he received maintenance ECT and stayed well for 13 months. Case 2 relapsed 4 months after a course of ECT. Acute and maintenance ECT induced improvement for 14 months. Further relapses were treated with brief courses of ECT followed by maintenance ECT. Three and 4 years after their first ECT, the parkinsonian motor symptoms in these two patients are still markedly improved. Neuropsychological assessments did not suggest ECT-induced long-term cognitive impairment. We conclude that maintenance ECT should be considered in PD patients who relapse after having responded to an initial course of ECT. There is an urgent need for controlled studies.
Authors:
D Aarsland; J P Larsen; O Waage; J H Langeveld
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Convulsive therapy     Volume:  13     ISSN:  0749-8055     ISO Abbreviation:  Convuls Ther     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-03-05     Completed Date:  1998-03-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8506311     Medline TA:  Convuls Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  274-7     Citation Subset:  IM    
Affiliation:
Section of Geriatric Psychiatry, Psychiatric Hospital of Rogland, Stavanger, Norway.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antiparkinson Agents / therapeutic use
Electroconvulsive Therapy* / adverse effects
Female
Fluvoxamine / therapeutic use
Functional Laterality
Humans
Informed Consent
Levodopa / therapeutic use
Male
Parkinson Disease / psychology,  therapy*
Serotonin Uptake Inhibitors / therapeutic use
Chemical
Reg. No./Substance:
0/Antiparkinson Agents; 0/Levodopa; 0/Serotonin Uptake Inhibitors; 54739-18-3/Fluvoxamine

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