Document Detail


Magnocellular and parvocellular developmental course in infants during the first year of life.
MedLine Citation:
PMID:  14711154     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The visual system undergoes major modifications during the first year of life. We wanted to examine whether the magnocellular (M) and parvocellular (P) pathways mature at the same rate or if they follow a different developmental course. A previous study carried out in our laboratory had shown that the N1 and P1 components of pattern visual evoked potentials (PVEPs) were preferentially related to the activity of P and M pathways, respectively. In the present study, PVEPs were recorded at Oz in 33 infants aged between 0 and 52 weeks, in response to two spatial frequencies (0.5 and 2.5 c deg(-1)) presented at four contrast levels (4, 12, 28 and 95%). Results indicate that the P1 component appeared before the N1 component in the periods tested and was unambiguously present at birth. The P1 component showed a rapid gain in amplitude in the following months, to reach a ceiling around 4-6 months. Conversely, the N1 component always appeared later and then gained in amplitude until the end of the first year without reaching a plateau. Latencies were also computed but no developmental dissociation was revealed. Results obtained on amplitude are interpreted as demonstrating a developmental dissociation between the underlying M and P pathways, suggesting that the former is functional earlier and matures faster than the latter during the first year of life.
Authors:
Benoit Hammarrenger; Franco Leporé; Sarah Lippé; Mélanie Labrosse; Jean-Paul Guillemot; Marie-Sylvie Roy
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Documenta ophthalmologica. Advances in ophthalmology     Volume:  107     ISSN:  0012-4486     ISO Abbreviation:  Doc Ophthalmol     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2004-01-08     Completed Date:  2004-02-04     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370667     Medline TA:  Doc Ophthalmol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  225-33     Citation Subset:  IM    
Affiliation:
Groupe de Recherche en Neuropsychologie Expérimentale, Département de Psychologie, Université de Montréal, Canada.
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MeSH Terms
Descriptor/Qualifier:
Contrast Sensitivity / physiology*
Evoked Potentials, Visual / physiology*
Humans
Infant
Infant, Newborn
Ocular Physiological Phenomena
Visual Pathways / physiology*

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