| Magnetoencephalography of focal cerebral ischemia in rats. | |
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MedLine Citation:
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PMID: 1519286 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: The purpose of this study was to use magnetoencephalography to record magnetic field changes in the brain during middle cerebral artery occlusion. METHODS: A direct-current electrocorticogram (two channels) and a direct-current magnetoencephalogram (seven channels) were simultaneously recorded from five rats subjected to middle cerebral artery occlusion for 1-2 hours. RESULTS: Direct-current electrocorticographic and direct-current magnetoencephalographic signal deflections were observed after the onset of middle cerebral artery occlusion and occurred repeatedly throughout the ischemic period, with a mean +/- SD time interval of 12 +/- 5 minutes. A one-to-one correspondence of the electrocorticographic and magnetoencephalographic signal deflections was demonstrated. CONCLUSIONS: Direct-current magnetoencephalography can provide a new noninvasive technique for studying depolarization and/or spreading depression in focal cerebral ischemia. |
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Authors:
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Q Chen; M Chopp; H Chen; N Tepley |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Stroke; a journal of cerebral circulation Volume: 23 ISSN: 0039-2499 ISO Abbreviation: Stroke Publication Date: 1992 Sep |
Date Detail:
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Created Date: 1992-10-06 Completed Date: 1992-10-06 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0235266 Medline TA: Stroke Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1299-303 Citation Subset: IM |
Affiliation:
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Department of Neurology, Henry Ford Hospital, Detroit, Mich. 48202. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Brain Ischemia / diagnosis* Cerebral Cortex / physiopathology Electroencephalography Magnetoencephalography* Male Rats Rats, Inbred Strains |
| Grant Support | |
ID/Acronym/Agency:
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NS23393/NS/NINDS NIH HHS; NS29463/NS/NINDS NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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