Document Detail


Magnetocardiography based spatiotemporal correlation analysis is superior to conventional ECG analysis for identifying myocardial injury.
MedLine Citation:
PMID:  19015988     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Electrocardiogram (ECG) particular from tiny, non Q-wave myocardial infarction may lack striking infarct pattern. Spatiotemporal correlation analysis (SCA) of multichannel magnetocardiogram (MCG) is a high-resolution "magnifying glass" to analyze homogeneity of repolarization. SCA involves full 4D spatiotemporal information to identify abnormalities as empirically done by eye in conventional ECG-but on an advanced level of analysis. We compared the discriminatory performance of SCA to ECG analysis in identifying myocardial infarction. Eleven SCA parameters were taken from signal averaged 31-channel MCG and compared to infarct indicators of ECG's in 178 subjects: 108 patients (76 males, mean age 62 years) after myocardial infarction (16-64 d) and 70 controls (36 males, mean age 46 years). SCA improves the detection of myocardial injury: in 72.5% ECG (sensitivity 68.6%, specificity 56%) and in 80.2% SCA parameters (sensitivity 72.6%, specificity 64%) separated patients from controls. SCA is applicable for the analysis of de- and repolarization of cardiac mapping data.
Authors:
Matthias Goernig; Mario Liehr; Christian Tute; Markus Schlosser; Jens Haueisen; H R Figulla; U Leder
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2008-11-18
Journal Detail:
Title:  Annals of biomedical engineering     Volume:  37     ISSN:  1573-9686     ISO Abbreviation:  Ann Biomed Eng     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-04     Completed Date:  2009-02-02     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  0361512     Medline TA:  Ann Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107-11     Citation Subset:  IM    
Affiliation:
Clinic of Internal Medicine I, Friedrich-Schiller-University Jena, Jena, Germany. Matthias.Goernig@med.uni-jena.de
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MeSH Terms
Descriptor/Qualifier:
Electrocardiography / methods
Heart Conduction System / physiopathology*
Humans
Magnetocardiography / methods
Male
Middle Aged
Myocardial Infarction / diagnosis*,  physiopathology
Signal Processing, Computer-Assisted

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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