| Magnetization-prepared IDEAL bSSFP: a flow-independent technique for noncontrast-enhanced peripheral angiography. | |
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MedLine Citation:
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PMID: 21448960 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To propose a new noncontrast-enhanced flow-independent angiography sequence based on balanced steady-state free precession (bSSFP) that produces reliable vessel contrast despite the reduced blood flow in the extremities. MATERIALS AND METHODS: The proposed technique addresses a variety of factors that can compromise the exam success including insufficient background suppression, field inhomogeneity, and large volumetric coverage requirements. A bSSFP sequence yields reduced signal from venous blood when long repetition times are used. Complex-sum bSSFP acquisitions decrease the sensitivity to field inhomogeneity but retain phase information, so that data can be processed with the Iterative Decomposition of Water and Fat with Echo Asymmetry and Least-Squares Estimation (IDEAL) method for robust fat suppression. Meanwhile, frequent magnetization preparation coupled with parallel imaging reduces the muscle and long-T(1) fluid signals without compromising scan efficiency. RESULTS: In vivo flow-independent peripheral angiograms with reliable background suppression and high spatial resolution are produced. Comparisons with phase-sensitive bSSFP angiograms (that yield out-of-phase fat and water signals, and exploit this phase difference to suppress fat) demonstrate enhanced vessel depiction with the proposed technique due to reduced partial-volume effects and improved venous suppression. CONCLUSION: Magnetization-prepared complex-sum bSSFP with IDEAL fat/water separation can create reliable flow-independent angiographic contrast in the lower extremities. |
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Authors:
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Tolga Cukur; Ann Shimakawa; Huanzhou Yu; Brian A Hargreaves; Bob S Hu; Dwight G Nishimura; Jean H Brittain |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 33 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-30 Completed Date: 2011-08-09 Revised Date: 2011-09-26 |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 931-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
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Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA. cukur@berkeley.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue
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metabolism Angiography / methods* Blood Flow Velocity Body Water / chemistry Calibration Contrast Media / pharmacology Diagnostic Imaging / methods Humans Least-Squares Analysis Magnetic Resonance Angiography / methods Magnetics Models, Statistical Risk Factors |
| Grant Support | |
ID/Acronym/Agency:
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R01 HL039297/HL/NHLBI NIH HHS; R01 HL039297-24/HL/NHLBI NIH HHS; R01 HL075803/HL/NHLBI NIH HHS; R01 HL075803-08/HL/NHLBI NIH HHS |
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Reg. No./Substance:
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0/Contrast Media |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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