| Magnetically immobilized beds for capillary electrochromatography. | |
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MedLine Citation:
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PMID: 17539602 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fritless packed beds comprised of magnetically responsive octadecylsilane bonded silica particles have been constructed for reversed-phase electrochromatography. The magnetic particles were immobilized in the capillary by applying an external magnetic field transverse to the direction of electroosmotic flow. Being subjected to the interplay of fluid dragging and magnetic forces, the initial loosely packed particle assembly was compacted into a uniform packing structure. The magnetically immobilized beds obtained were used as stationary phases for separation of neutral compounds, with retention behavior and column efficiency similar to those of slurry-packed columns. The results suggest that the magnetic attraction approach to fritless column packing may be used for construction of advanced chip-based chromatography, especially in complex architectures comprising curved and intersecting channels. |
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Authors:
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Yucong Wang; Zhichao Zhang; Lei Zhang; Feng Li; Lei Chen; Qian-Hong Wan |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-06-01 |
Journal Detail:
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Title: Analytical chemistry Volume: 79 ISSN: 0003-2700 ISO Abbreviation: Anal. Chem. Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-06-29 Completed Date: 2007-09-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370536 Medline TA: Anal Chem Country: United States |
Other Details:
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Languages: eng Pagination: 5082-6 Citation Subset: IM |
Affiliation:
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School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anthracenes
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isolation & purification Capillary Electrochromatography / instrumentation, methods* Electromagnetic Fields* Electroosmosis Equipment Design Nanoparticles / chemistry* Silanes / chemistry* Silicon Dioxide / chemistry* Thiourea / isolation & purification |
| Chemical | |
Reg. No./Substance:
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0/Anthracenes; 0/Silanes; 120-12-7/anthracene; 18623-11-5/octadecylsilane; 62-56-6/Thiourea; 7631-86-9/Silicon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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