| Magnetic susceptibility shift selected imaging: MESSI. | |
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MedLine Citation:
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PMID: 2255239 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Paramagnetic compounds are often used to enhance contrast in MRI by virtue of their increase in the kinetics of the relaxation of water 1H magnetization. Here, we demonstrate a method for contrast enhancement which is based on the resonance frequency shifts caused by the bulk magnetic susceptibility (BMS) effects of such compounds. This involves the frequency selective excitation in the absence of field gradients, during the imaging sequence, of a portion of the water 1H resonance which is rendered inhomogeneous by BMS shifts only. The image which results is of that portion of the sample which gives rise to the portion of the spectrum excited. A phantom sample which simulates some aspects of tissue, particularly blood vessels with different orientations in the magnetic field, was prepared. The contrast enhancement exhibited here avoids some of the distortions attendant to the use of paramagnetic reagents. This new approach can, in principle, utilize the natural BMS differences found in all tissue. |
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Authors:
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Y Xu; J A Balschi; C S Springer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: 16 ISSN: 0740-3194 ISO Abbreviation: Magn Reson Med Publication Date: 1990 Oct |
Date Detail:
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Created Date: 1991-01-18 Completed Date: 1991-01-18 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 80-90 Citation Subset: IM |
Affiliation:
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Department of Chemistry, State University of New York, Stony Brook 11794-3400. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Vessels / anatomy & histology Fourier Analysis Image Enhancement / methods* Magnetic Resonance Imaging / instrumentation, methods* Magnetic Resonance Spectroscopy Magnetics* Models, Anatomic Sodium Chloride Tritium Water |
| Grant Support | |
ID/Acronym/Agency:
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GM 32125/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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10028-17-8/Tritium; 7647-14-5/Sodium Chloride; 7732-18-5/Water |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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