Document Detail


Magnetic source MRI: A new quantitative imaging of magnetic biomarkers.
MedLine Citation:
PMID:  19965112     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A new approach to generating MRI contrast by solving the magnetic field to susceptibility source inverse problem is presented to address the quantification difficulties associated with traditional T1/T2 relaxation and susceptibility weighted T2 * methods. The forward problem from source to field is reviewed. Its inverse field to source problem is ill posed. Accurate solutions are found by conditioning the data acquisition or regularizing the solution. Preclinical and clinical applications using this magnetic source MRI are discussed for quantitative mapping magnetic biomarkers such as contrast agents in molecular MRI and iron deposits in diseases.
Authors:
Yi Wang; Ludovic de Rochefort; Tian Liu; Bryan Kressler
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference     Volume:  1     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  53-6     Citation Subset:  IM    
Affiliation:
Radiology and Biomedical Engineering, Cornell University, 416 East 55 Street, New York, NY 10022.
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