Document Detail

Magnetic resonance to assess the aortic valve area in aortic stenosis: how does it compare to current diagnostic standards?
MedLine Citation:
PMID:  12906983     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: The purpose of the present study was to evaluate whether magnetic resonance (MR) planimetry of the aortic valve area (AVA) may prove to be a reliable, non-invasive diagnostic tool in the assessment of aortic valve stenosis, and how the results compare with current diagnostic standards. BACKGROUND: Current standard techniques for assessing the severity of aortic stenosis include transthoracic and transesophageal echocardiography (TEE) as well as transvalvular pressure measurements during cardiac catheterization. METHODS: Forty consecutive patients underwent cardiac catheterization, TEE, and MR. The AVA was estimated by direct planimetry (MR, TEE) or calculated indirectly via the peak systolic transvalvular gradient (catheter). Pressure gradients from cardiac catheterization and Doppler echocardiography were also compared. RESULTS: By MR, the mean AVA(max) was 0.91 +/- 0.25 cm(2); by TEE, AVA(max) was 0.89 +/- 0.28 cm(2); and by catheter, the AVA was calculated as 0.64 +/- 0.26 cm(2). Mean absolute differences in AVA were 0.02 cm(2) for MR versus TEE, 0.27 cm(2) for MR versus catheter, and 0.25 cm(2) for TEE versus catheter. Correlations for AVA(max) were r = 0.96 between MR and TEE, r = 0.47 between TEE and catheter, and r = 0.44 between MR and catheter. The correlation between Doppler and catheter gradients was r = 0.71. CONCLUSIONS: Magnetic resonance planimetry of the AVA correlates well with TEE and less well with the catheter-derived AVA. Invasive and Doppler pressure correlated less well than those obtained from planimetric techniques. Magnetic resonance planimetry of the AVA may provide an accurate, non-invasive, well-tolerated alternative to invasive techniques and transthoracic echocardiography in the assessment of aortic stenosis.
Anna S John; Thorsten Dill; Roland R Brandt; Matthias Rau; Wolfgang Ricken; Georg Bachmann; Christian W Hamm
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  42     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-08-08     Completed Date:  2003-09-11     Revised Date:  2010-03-23    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  519-26     Citation Subset:  AIM; IM    
Department of Cardiology, Kerckhoff Clinic, Bad, Nauheim, Germany.
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MeSH Terms
Aged, 80 and over
Anatomy, Cross-Sectional
Aortic Valve / anatomy & histology*
Aortic Valve Stenosis / diagnosis*,  ultrasonography
Body Weights and Measures
Echocardiography, Transesophageal
Heart Catheterization
Magnetic Resonance Imaging* / methods
Middle Aged
Comment In:
J Am Coll Cardiol. 2004 Jun 2;43(11):2148; author reply 2148-9   [PMID:  15172429 ]

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