| Magnetic resonance reveals long-term sequelae of apical ballooning syndrome. | |
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MedLine Citation:
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PMID: 18804880 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The presence of small areas of necrosis has been occasionally reported immediately following apical ballooning syndrome (ABS). However, their persistence at later stages and impact on long-term prognosis are currently unknown. METHODS: Twenty consecutive patients admitted for ABS between 2004 and 2007 were prospectively evaluated. Demographic, clinical, angiographic, and echocardiographic data were collected during hospital admission. At a mean of 11+/-9 months follow-up, a contrast enhanced cardiac magnetic resonance (ce-CMR) study was performed in 17 cases. The presence of hyperenhancement on ce-CMR images, reflecting irreversible myocardial damage, was recorded by two independent observers. RESULTS: Two of 3 patients with hyperenhancement on ce-CMR images presented in worse condition, including pulmonary edema or cardiogenic shock, compared to just 2 of 14 patients without hyperenhancement (p=0.052). Segmental wall motion substantially improved in both of those cases; the third patient continued to have hypokinesis in a segment showing hyperenhancement. Segmental wall motion also significantly improved in all patients with no hyperenhancement. At a mean of 20+/-12 months follow-up, no deaths or major adverse cardiac events were documented among patients with or without hyperenhancement. CONCLUSIONS: Despite segmental wall motion recovery, an area of irreversible myocardial damage can sometimes be identified long after ABS. However, in this limited series of patients, the presence of scar, even when presenting with heart failure and a higher troponin release, was not associated with adverse long-term outcomes as compared to patients with intact myocardium. |
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Authors:
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M Neus Bellera; Jos? T Ortiz; Maria Teresa Caralt; Jordi P?rez-Rodon; Jaume Mercader; Carlos Fern?ndez-G?mez; Carles Par?; Magda Heras |
Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't Date: 2008-09-19 |
Journal Detail:
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Title: International journal of cardiology Volume: 139 ISSN: 1874-1754 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-17 Completed Date: 2010-05-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 25-31 Citation Subset: IM |
Copyright Information:
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Copyright 2008 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Thorax Institute, IDIBAPS, Barcelona, Spain. mbellera_gotarda@hotmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Cicatrix / epidemiology, pathology, ultrasonography Contrast Media / diagnostic use Echocardiography Electrocardiography Female Follow-Up Studies Humans Life Change Events Magnetic Resonance Imaging / methods* Male Middle Aged Morbidity Myocardium / pathology Predictive Value of Tests Prognosis Prospective Studies Pulmonary Edema / epidemiology, pathology, ultrasonography Recovery of Function Shock, Cardiogenic / epidemiology, pathology, ultrasonography Takotsubo Cardiomyopathy / epidemiology, pathology*, ultrasonography* Troponin / blood Ventricular Function, Left |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Troponin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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