Document Detail

Magnetic resonance in multiple sclerosis.
MedLine Citation:
PMID:  3762909     Owner:  NLM     Status:  MEDLINE    
Magnetic Resonance Imaging was performed in more than 200 patients with clinical suspicion or knowledge of Multiple Sclerosis. One hundred and forty-seven (60 males and 87 females) had MR evidence of multiple sclerosis lesions. The MR signal of demyelinating plaques characteristically has prolonged T1 and T2 relaxation times and the T2-weighted spin-echo sequences are generally superior to the T1-weighted images because the lesions are better visualized as areas of increased signal intensity. MR is also able to detect plaques in the brainstem, cerebellum and within the cervical spinal cord. MR appears to be an important, non-invasive method for the diagnosis of Multiple Sclerosis and has proven to be diagnostically superior to CT, evoked potentials (EP) and CSF examination. In a selected group of 30 patients, with the whole battery of the relevant MS studies, MR was positive in 100%, CT in 33.3%, EP in 56% and CSF examination in 60%. In patients clinically presenting only with signs of spinal cord involvement or optic neuritis or when the clinical presentation is uncertain MR has proven to be a very useful diagnostic tool for diagnosis of MS by demonstrating unsuspected lesions in the cerebral hemispheres.
G Scotti; G Scialfa; A Biondi; L Landoni; D Caputo; C L Cazzullo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuroradiology     Volume:  28     ISSN:  0028-3940     ISO Abbreviation:  Neuroradiology     Publication Date:  1986  
Date Detail:
Created Date:  1986-11-12     Completed Date:  1986-11-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1302751     Medline TA:  Neuroradiology     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  319-23     Citation Subset:  IM    
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MeSH Terms
Magnetic Resonance Spectroscopy*
Multiple Sclerosis / diagnosis*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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