| Magnetic resonance imaging of primary breast lymphoma. | |
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MedLine Citation:
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PMID: 19562266 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Primary lymphomas of the breast (PBNHL) are uncommon. Magnetic resonance imaging (MRI) features of these malignancies can be relevant in establishing the extent of disease and planning the appropriate therapeutic strategy, usually represented by chemo- and radiotherapy, rather than surgery. The purpose of this study was to assess MRI features of PBNHL. MATERIALS AND METHODS: MRI examinations performed on seven patients with known PBNHL were retrospectively evaluated. Lesions were analysed for both morphology and kinetics and classified according to the Breast Imaging Reporting and Data System (BI-RADS) categories. RESULTS: The mean MRI maximum diameter was 44 mm (range 12-69). Six lesions showed a mass-like enhancement; one lesion showed a non-mass-like enhancement. For mass-like lesions, kinetic curve assessment of initial rise showed slow enhancement in one lesion, rapid enhancement in four lesions and medium enhancement in one lesion. Assessment of delayed enhancement showed plateau in five lesions and washout in one lesion. MRI BI-RADS categories were distributed as follows: one BI-RADS II, one BI-RADS III, three BI-RADS IV and two BI-RADS V. CONCLUSIONS: MRI features of primary breast lymphomas in this study cohort suggest that the occurrence of a PBNHL should be considered in the presence of large enhancing lesions of the breast, especially if associated with skin thickening. MRI may also have an important role in the assessment of response to therapy and diagnosis of recurrence. |
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Authors:
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S Rizzo; L Preda; G Villa; S Brambilla; G Pruneri; A Alietti; E Cassano; G Martinelli; M Bellomi |
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Publication Detail:
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Type: Journal Article Date: 2009-06-26 |
Journal Detail:
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Title: La Radiologia medica Volume: 114 ISSN: 1826-6983 ISO Abbreviation: Radiol Med Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-10-02 Completed Date: 2009-12-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0177625 Medline TA: Radiol Med Country: Italy |
Other Details:
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Languages: eng; ita Pagination: 915-24 Citation Subset: IM |
Affiliation:
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Department of Radiology, European Institute of Oncology, Via Ripamonti 435, 20141 Milan, Italy. stefania.rizzo@ieo.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Breast Neoplasms / diagnosis*, pathology Contrast Media Female Gadolinium DTPA / diagnostic use Humans Image Enhancement / methods Image Interpretation, Computer-Assisted / methods Lymphoma / diagnosis*, pathology Magnetic Resonance Imaging / methods* Middle Aged Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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