Document Detail

Magnetic resonance imaging of peripheral joints in rheumatic diseases.
MedLine Citation:
PMID:  15501187     Owner:  NLM     Status:  MEDLINE    
The need for better methods than the conventional clinical, biochemical and radiographical examinations in the management of inflammatory joint diseases is evident, since these methods are not sensitive or specific to early pathologies and subtle changes. Magnetic resonance imaging (MRI) offers improved sensitivity to early inflammatory and destructive changes in peripheral joints in rheumatoid arthritis (RA) and, even though less well documented, in other inflammatory joint diseases. Good evidence is available that MRI bone erosions represent true bone abnormalities and are predictors of radiographical outcome in RA. Similarly, there is solid evidence for MRI synovitis representing true synovial inflammation and being of considerable practical, clinical and radiological significance in RA. Describing the encouraging current knowledge regarding MRI for diagnosis, monitoring and prognosis, this chapter discusses the potential for the use of MRI in the clinical management of patients with suspected and diagnosed inflammatory joint diseases, as well as research priorities and clinical situations where the use of MRI could be suggested.
Mikkel Østergaard; Anne Duer; Uffe Møller; Bo Ejbjerg
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Best practice & research. Clinical rheumatology     Volume:  18     ISSN:  1521-6942     ISO Abbreviation:  Best Pract Res Clin Rheumatol     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-10-25     Completed Date:  2005-02-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101121149     Medline TA:  Best Pract Res Clin Rheumatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  861-79     Citation Subset:  IM    
Department of Rheumatology, Copenhagen University Hospitals at Herlev and Hvidovre, Kettegaard alle 30, DK-2650 Hvidovre, Copenhagen, Denmark.
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MeSH Terms
Joints / pathology*
Magnetic Resonance Imaging*
Rheumatic Diseases / diagnosis*
Rheumatology / methods

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