Document Detail

Magnetic resonance imaging for myocardial viability.
MedLine Citation:
PMID:  20542816     Owner:  NLM     Status:  MEDLINE    
Detection of myocardial viability is an important issue that needs to be addressed when patients with dysfunctional myocardium are considered to be revascularised. The pathophysiological substrate may include myocardial hibernation, myocardial stunning, or both. The greatest benefit is in terms of myocardial function recovery and prognosis is obtained if the revascularised vascular territory contains viable myocardium. Viable myocardium can be detected with nuclear techniques (SPECT, PET), low dose dobutamine stress echocardiography and MRI. With MRI robust detection of viable myocardium can be performed with delayed enhancement (with gadolinium contrast agent), low dose dobutamine stress, and stress/rest perfusion imaging. For recovery of myocardial function there are relatively small differences between all available techniques, whereas for improvement of prognosis all techniques perform equally. Myocardial delayed enhancement imaging can also visualise micro-embolisation as a result of percutaneous coronary intervention. Furthermore, MRI delayed enhancement enables differentiation between ischaemic and non-ischaemic heart disease and can identify specific cardiomyopathies.
Hans-Marc J Siebelink; Hildo J Lamb
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology     Volume:  6 Suppl G     ISSN:  1969-6213     ISO Abbreviation:  EuroIntervention     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-06-14     Completed Date:  2010-09-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101251040     Medline TA:  EuroIntervention     Country:  France    
Other Details:
Languages:  eng     Pagination:  G107-14     Citation Subset:  IM    
Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary
Contrast Media / diagnostic use
Coronary Circulation
Dobutamine / diagnostic use
Heart Diseases / diagnosis*,  pathology,  physiopathology,  therapy
Magnetic Resonance Imaging*
Myocardial Perfusion Imaging / methods*
Myocardium / pathology*
Predictive Value of Tests
Recovery of Function
Tissue Survival
Treatment Outcome
Ventricular Function, Left
Reg. No./Substance:
0/Contrast Media; 34368-04-2/Dobutamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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