Document Detail


Magnetic resonance imaging morphometry of the midbrain in patients with Wilson disease.
MedLine Citation:
PMID:  16272867     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study, the focus is on midbrain magnetic resonance imaging morphometric measures (transverse diameter of the midbrain peduncle [Tp], transverse diameter of the tegmentum, anteroposterior diameter of the midbrain, interpeduncular distance [IPD], and interpeduncular angle [IPA]) in a group of 47 consecutive patients with neurologic (37 patients) and hepatic (10 patients) forms of Wilson disease (WD). Morphometric measures were significantly different between the group of patients with WD and healthy controls (51 subjects) as well as patients with Parkinson disease (15 patients) and multiple sclerosis (15 patients). Among the studied variables, IPA, Tp, and IPD were particularly useful in differentiating patients from healthy subjects (probability reaching 93%).
Authors:
Robert Semnic; Marina Svetel; Natasa Dragasevic; Igor Petrovic; Dusko Kozic; Jelena Marinkovic; Vladimir S Kostic; R Nuri Sener
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  29     ISSN:  0363-8715     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2005 Nov-Dec
Date Detail:
Created Date:  2005-11-07     Completed Date:  2005-12-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  880-3     Citation Subset:  IM    
Affiliation:
Center for Magnetic Resonance Imaging, Sremska Kamenica, Serbia.
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MeSH Terms
Descriptor/Qualifier:
Adult
Analysis of Variance
Atrophy / diagnosis,  etiology
Brain Mapping / methods
Discriminant Analysis
Female
Hepatolenticular Degeneration / complications,  diagnosis*
Humans
Magnetic Resonance Imaging / methods*
Male
Mesencephalon / pathology*
Middle Aged
Reference Values

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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