Document Detail


Magnetic resonance imaging in spondyloarthritis--how to quantify findings and measure response.
MedLine Citation:
PMID:  21035085     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Sensitive and reliable tools for monitoring disease activity and damage, and for prognostication, are essential in the management of patients with spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis. Magnetic resonance imaging (MRI) allows direct visualisation of inflammation in peripheral and axial joints, and peripheral and axial entheses, and has dramatically improved the possibilities for early diagnosis and objective monitoring of the disease process in spondyloarthritis. Truthful, discriminative and feasible scoring systems are available for the assessment of inflammatory activity in the spine and sacroiliac joints in axial spondyloarthritis and in the hands of patients with peripheral psoriatic arthritis. Various systems for assessment of damage in axial and peripheral joints are available, but further studies are needed to document their value in clinical trials and clinical practice. The present article reviews key aspects of the status and recent important advances in MRI in spondyloarthritis, focussing on available MRI tools for assessing activity and damage in peripheral and, particularly, axial joints.
Authors:
Mikkel Ostergaard; René Panduro Poggenborg; Mette Bjørndal Axelsen; Susanne Juhl Pedersen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Best practice & research. Clinical rheumatology     Volume:  24     ISSN:  1532-1770     ISO Abbreviation:  Best Pract Res Clin Rheumatol     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-11-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101121149     Medline TA:  Best Pract Res Clin Rheumatol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  637-57     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Rheumatology, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark. mo@dadlnet.dk
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