| Magnetic resonance imaging in local staging of endometrial carcinoma: diagnostic performance, pitfalls, and literature review. | |
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MedLine Citation:
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PMID: 20968141 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS AND BACKGROUND: To assess the diagnostic accuracy of magnetic resonance imaging in local staging of endometrial carcinoma, and to review the results and pitfalls described in the literature. METHODS: Thirty women with a histological diagnosis of endometrial carcinoma underwent magnetic resonance imaging. Unenhanced T2-weighted and dynamic contrast-enhanced Ti-weighted sequences were obtained. Hysterectomy and salpingo-oophorectomy was performed in all patients. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated for the detection of deep myometrial and cervical infiltration. RESULTS: For deep myometrial infiltration T2-weighted sequences reached a sensitivity of 85%, specificity of 76%, PPV of 73%, NVP of 87%, and accuracy of 80%, while contrast-enhanced scans reached a sensitivity of 90%, specificity of 80%, PPV of 82%, NPV of 89%, and accuracy of 85%. For cervical infiltration T2-weighted sequences reached a sensitivity of 75%, specificity of 88%, PPV of 50%, NPV of 96%, and accuracy of 87%, while contrast-enhanced scans reached a sensitivity of 100%, specificity of 94%, PPV of 75%, NPV of 100%, and accuracy of 95%. CONCLUSIONS: Unenhanced and dynamic gadolinium-enhanced magnetic resonance allows accurate assessment of myometrial and cervical infiltration. Information provided by magnetic resonance imaging can define prognosis and management. |
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Authors:
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Franco Zandrino; Ernesto La Paglia; Francesco Musante |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Tumori Volume: 96 ISSN: 0300-8916 ISO Abbreviation: Tumori Publication Date: 2010 Jul-Aug |
Date Detail:
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Created Date: 2010-10-25 Completed Date: 2010-11-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0111356 Medline TA: Tumori Country: Italy |
Other Details:
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Languages: eng Pagination: 601-8 Citation Subset: IM |
Affiliation:
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Department of Radiology, Azienda Ospedaliera 55 Antonio e Biagio e C. Arrigo, Alessandria, Italy. zandrino@libero.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Contrast Media / diagnostic use Endometrial Neoplasms / pathology*, surgery Female Humans Hysterectomy Magnetic Resonance Imaging* / methods Middle Aged Neoplasm Staging / methods Ovariectomy Predictive Value of Tests Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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