Document Detail

Magnetic resonance imaging in children receiving quinolones: no evidence of quinolone-induced arthropathy. A multicenter survey.
MedLine Citation:
PMID:  8205939     Owner:  NLM     Status:  MEDLINE    
Twenty-nine children with cystic fibrosis (CF) were investigated for quinolone-induced arthropathy. Magnetic resonance imaging (MRI) was performed in 14/14 children treated with ofloxacin or ciprofloxacin and in 10/15 of those never treated with quinolones. The frequency of pathologic MRI findings, concerning cartilage thickness, careful analysis of the cartilage structure, presence of edema, cartilage-bone borderline and the presence of fluid in joints did not show any difference between both groups. Thus the presence of quinolone-induced arthrotoxicity cannot be confirmed in this study.
A Danisovicová; M Brezina; S Belan; H Kayserová; E Kaiserová; I Hruskovic; K Orosová; S Dluholucký; K Galova; E Mathéova
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study    
Journal Detail:
Title:  Chemotherapy     Volume:  40     ISSN:  0009-3157     ISO Abbreviation:  Chemotherapy     Publication Date:    1994 May-Jun
Date Detail:
Created Date:  1994-07-14     Completed Date:  1994-07-14     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0144731     Medline TA:  Chemotherapy     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  209-14     Citation Subset:  IM    
Department of Pediatric Nursing, Postgraduate Medical School, Bratislava, Slovak Republic.
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MeSH Terms
Cartilage, Articular / pathology
Ciprofloxacin / adverse effects*
Cystic Fibrosis / complications*
Joint Diseases / chemically induced*
Knee Joint / pathology
Magnetic Resonance Imaging
Ofloxacin / adverse effects*
Reg. No./Substance:
82419-36-1/Ofloxacin; 85721-33-1/Ciprofloxacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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