Document Detail

Magnetic resonance imaging findings of neuroaxonal dystrophy in a papillon puppy.
MedLine Citation:
PMID:  17543020     Owner:  NLM     Status:  MEDLINE    
A 3.5-month-old papillon puppy was brought to our clinic with chief complaints of progressive quadriparesis, ataxia and head tremor. Lesions in the cerebellum, brainstem and spinal cord were suspected on the basis of a neurological examination. No abnormality was found in a clinicopathological examination or on magnetic resonance imaging. On the basis of these results differential diagnoses including an inflammatory disease, a degenerative condition or a storage disorder were considered. Subsequently, the signs progressed and glossoplegia and dysphagia developed at six months of age. At a second magnetic resonance imaging, severe atrophy of the entire brain was found. After these examinations, the puppy was euthanased and histopathologically diagnosed with neuroaxonal dystrophy. Because magnetic resonance imaging detected abnormal features that were characteristic of neuroaxonal dystrophy in this case, we speculate that magnetic resonance imaging can assist in the pre-mortem diagnosis of this disease.
S Tamura; Y Tamura; K Uchida
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-06-02
Journal Detail:
Title:  The Journal of small animal practice     Volume:  48     ISSN:  0022-4510     ISO Abbreviation:  J Small Anim Pract     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-07-31     Completed Date:  2007-09-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0165053     Medline TA:  J Small Anim Pract     Country:  England    
Other Details:
Languages:  eng     Pagination:  458-61     Citation Subset:  IM    
Tamura Animal Clinic, 7-16 Yoshimien, Saeki-ku, Hiroshima, Japan.
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MeSH Terms
Animals, Newborn
Diagnosis, Differential
Dog Diseases / diagnosis*,  pathology
Magnetic Resonance Imaging / veterinary
Neuroaxonal Dystrophies / diagnosis,  veterinary*
Neurologic Examination / veterinary

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