| Magnetic resonance imaging findings in epileptic children and its relation to clinical and demographic findings. | |
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MedLine Citation:
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PMID: 22267377 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Epilepsy is an important disease with a cumulative incidence of 3% all over the life and more than half of them are started from childhood. In this study we surveyed magnetic resonance imaging (MRI) findings in epileptic children and its relation with clinical and demographic findings in order to find better diagnostic and treatment modalities for these children in the future. In this cross sectional study, we investigated consecutively all 1 to 15-year-old epileptic children who referred to the pediatric neurology outpatient clinic from 2004 to 2010. Two hundred children were enrolled for investigation. There were 85 (42.5%) girls and 115 (57.7%) boys, aged 1 to 15-year-old (7.7±4). 196 (98%) of the children had abnormal electroencephalography (EEG). Abnormal MRI was seen in 57 (28.5%) patients and consisted of brain atrophy (10%), increasing white matter signal intensity in T2-weighted images (8%), benign cysts (5%), brain tumors (4%) and vascular abnormalities (1.5%). Abnormal MRI findings had significant relation with abnormal EEG, age, positive family history for epilepsy, dysmorphic appearance, and abnormal physical exam. Considering 98% EEG abnormalities in these epileptic children, benign nature of MRI findings in most of our cases, the high price of MRI and the small minority of patients who benefit from active intervention as a result of MRI, we suggest to use EEG for confirmation of epilepsy and perform MRI for patient with abnormal physical exams, focal neurologic deficits or focal EEG abnormalities. |
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Authors:
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Susan Amirsalari; Amin Saburi; Reza Hadi; Mohammad Torkaman; Fatemeh Beiraghdar; Shahla Afsharpayman; Yasaman Ghazavi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta medica Iranica Volume: 50 ISSN: 1735-9694 ISO Abbreviation: Acta Med Iran Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-01-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 14540050R Medline TA: Acta Med Iran Country: Iran |
Other Details:
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Languages: eng Pagination: 37-42 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Baqiyatallah University of Medical Sciences, Tehran, Tehran, Iran. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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