Document Detail

Magnetic resonance imaging features of pathologically proven cerebral sparganosis.
MedLine Citation:
PMID:  23680666     Owner:  NLM     Status:  Publisher    
OBJECTIVE: The purpose of this study was to identify characteristic magnetic resonance imaging (MRI) features of cerebral sparganosis, a rare parasitic disease caused by the plerocercoid larva of Spirometra mansoni. METHODS: This retrospective study reviewed medical records, computed tomography (CT) and MRI scans and pathological specimens from patients with pathologically proven cerebral sparganosis. The location, signal intensity and contrast enhancement characteristics of the lesions were assessed. RESULTS: Records of 12 patients (seven male and five female; age range 8-35 years) were reviewed. A total of 13 lesions were identified: of the 10 patients with supratentorial lesions, nine had a single lesion and one had bilateral hemispheric lesions. Two patients had a single lesion in the ependyma of the 4(th) ventricle. All lesions were iso-hypointense on T1-weighted images, slightly hypointense on T2-weighted images and surrounded by extensive oedema. Ten of the 13 lesions demonstrated a 'string-knots sign', characterized by a tangled string in a knot-like shape on contrast-enhanced MRI. CONCLUSION: A string-knots sign enhancement pattern in cortical-subcortical regions should suggest the diagnosis of cerebral sparganosis.
Shuguang Chu; Xingsui Lu; Yin Wang; Gejun Gao; Feijia Xv; Chi-Shing Zee; Zhenwei Yao
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-5-16
Journal Detail:
Title:  The Journal of international medical research     Volume:  -     ISSN:  1473-2300     ISO Abbreviation:  J. Int. Med. Res.     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-5-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0346411     Medline TA:  J Int Med Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Radiology, Huashan Hospital, Shanghai, China.
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