| Magnetic resonance imaging determination of cardiac prognosis. | |
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MedLine Citation:
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PMID: 12403662 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Regional assessments of left ventricular (LV) wall motion obtained during MRI cardiac stress tests can be used to identify myocardial injury and ischemia, but the utility of MRI stress test results for the assessment of cardiac prognosis is not known. METHODS AND RESULTS: Two hundred seventy-nine patients referred (because of poor LV endocardial visualization with echocardiography) for dobutamine/atropine MRI for the detection of inducible ischemia were followed for an average of 20 months. After MRI stress testing, the occurrence of myocardial infarction, cardiac death, death attributable to any cause, coronary arterial revascularization, and unstable angina or congestive heart failure requiring hospitalization was determined. In a multivariate analysis, the presence of inducible ischemia (hazard ratio 3.3, CI 1.1 to 9.7) or an LV ejection fraction <40% (hazard ratio 4.2, CI 1.3 to 13.9) was associated with future MI or cardiac death independent of the presence of risk factors for coronary arteriosclerosis. CONCLUSIONS: In patients with poor echocardiograms, the results of cardiac MRI stress tests can be used to forecast myocardial infarction or cardiac death. |
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Authors:
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W Gregory Hundley; Timothy M Morgan; Christina M Neagle; Craig A Hamilton; Pairoj Rerkpattanapipat; Kerry M Link |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Circulation Volume: 106 ISSN: 1524-4539 ISO Abbreviation: Circulation Publication Date: 2002 Oct |
Date Detail:
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Created Date: 2002-10-29 Completed Date: 2002-11-04 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0147763 Medline TA: Circulation Country: United States |
Other Details:
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Languages: eng Pagination: 2328-33 Citation Subset: AIM; IM |
Affiliation:
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Department of Internal Medicine (Cardiology Section), Wake Forest University School of Medicine, Winston-Salem, NC 27157-1045, USA. ghundley@wfubmc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Atropine / diagnostic use Death, Sudden, Cardiac / etiology, prevention & control Disease-Free Survival Dobutamine / diagnostic use Exercise Test Female Follow-Up Studies Heart Diseases / complications, diagnosis* Heart Function Tests Humans Magnetic Resonance Imaging* Male Middle Aged Myocardial Infarction / etiology, prevention & control Myocardial Ischemia / diagnosis, etiology Odds Ratio Predictive Value of Tests Prognosis Risk Assessment Stroke Volume Ventricular Function, Left |
| Grant Support | |
ID/Acronym/Agency:
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3-M01-RR07122-08S1/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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34368-04-2/Dobutamine; 51-55-8/Atropine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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