Document Detail


Magnetic resonance imaging of cyclodialysis clefts.
MedLine Citation:
PMID:  9248845     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Our purpose was to determine whether cyclodialysis clefts can be imaged with magnetic resonance imaging (MRI). METHODS: Surgical cyclodialysis clefts extending approximately 3 clock hours were created in four New Zealand white rabbits. Eyes were scanned with an ocular MRI coil. Images obtained after intravenous gadolinium, topical godalinium, and gadolinium injected into the cleft were compared to images obtained without contrast. Two human eyes were also scanned for cyclodialysis clefts with MRI. RESULTS: Direct injection of gadolinium into the suprachoroid space yielded definitive localization and delineation of the cyclodialysis cleft. Cyclodialysis clefts could also be imaged following enhancement with topical or intravenous gadolinium. Without contrast medium, the clefts could not be clearly identified in rabbits. In a patient with hypotony and choroidal effusion following cataract surgery, a cyclodialysis cleft and enhancement of the suprachoroidal space were found with intravenous administration of gadolinium. MRI from a patient with a trabeculo-suprachoroidal shunt also demonstrated gadolinium enhancement of the suprachoroidal space. CONCLUSION: Cyclodialysis clefts can be imaged using gadolinium-enhanced MRI in rabbits and humans.
Authors:
S M Johnson; H M Cheng; R Pineda; P A Netland
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie     Volume:  235     ISSN:  0721-832X     ISO Abbreviation:  Graefes Arch. Clin. Exp. Ophthalmol.     Publication Date:  1997 Jul 
Date Detail:
Created Date:  1997-09-17     Completed Date:  1997-09-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8205248     Medline TA:  Graefes Arch Clin Exp Ophthalmol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  468-71     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Animals
Ciliary Body / injuries*,  pathology
Eye Injuries / diagnosis*
Female
Gadolinium / diagnostic use
Humans
Image Enhancement
Magnetic Resonance Imaging*
Male
Rabbits
Radioisotopes / diagnostic use
Grant Support
ID/Acronym/Agency:
EY08925/EY/NEI NIH HHS
Chemical
Reg. No./Substance:
0/Radioisotopes; 7440-54-2/Gadolinium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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