Document Detail


Magnetic resonance imaging for axillary staging in patients with breast cancer.
MedLine Citation:
PMID:  19466713     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine the utility of MRI for assessing axillary lymph node status in patients with breast cancer. MATERIALS AND METHODS: A consecutive series of patients who underwent breast MR before surgical management of breast cancer with axillary sampling between 2005 and 2007 were identified. MRs were evaluated for the number of nodes, contrast kinetics, nodal area, and number of nodes with no fatty hilum. Data were analyzed in the context of final breast pathology, sentinel lymph node status, and axillary nodal status. Correlations were analyzed using Kendall's tau-b test. Reported P values are one-sided. RESULTS: Fifty-six females (median = 58 years) were studied. Sentinel lymph nodes (SLN) were positive in 15/56 patients (27%). All SLN + patients (n = 15) had completion axillary dissection. Extent of nodal disease was 1 (n = 3), 2 (n = 4), >2 (n = 8). Presence of any axillary lymph node with no fatty hilum and the number of nodes with no fatty hilum on MR significantly correlated with pathologic node positivity (P = 0.04); while kinetics, node number, and node size did not correlate. CONCLUSION: Breast MR may be useful in the assessment of axillary nodes in patients with breast cancer.
Authors:
Vincent E Mortellaro; Julia Marshall; Lauren Singer; Steven N Hochwald; Myron Chang; Edward M Copeland; Stephen R Grobmyer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  30     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-29     Completed Date:  2009-09-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  309-12     Citation Subset:  IM    
Copyright Information:
(c) 2009 Wiley-Liss, Inc.
Affiliation:
Division of Surgical Oncology, Department of Surgery, University of Florida, Gainesville, Florida 32610, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Axilla
Breast Neoplasms / pathology*
Contrast Media
Female
Gadolinium DTPA / diagnostic use
Humans
Image Interpretation, Computer-Assisted
Lymph Nodes / pathology*
Lymphatic Metastasis / pathology
Magnetic Resonance Imaging / methods*
Middle Aged
Neoplasm Staging
Sentinel Lymph Node Biopsy
Chemical
Reg. No./Substance:
0/Contrast Media; 122795-43-1/gadodiamide; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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