| Magnetic resonance imaging for assessment of treatment effects in mediastinal Hodgkin's disease. | |
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MedLine Citation:
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PMID: 2953367 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Six patients with mediastinal involvement of Hodgkin's disease were examined with magnetic resonance imaging (MRI) at 0.35 T before and/or at various stages of therapy, with the sequences TR/TE: 500/35, 500/70, 1600/35 and 1,600/70. Before therapy the image intensity of tumour involved lymph nodes deviated considerably from fat and muscle, but no clear difference was discerned between histopathologic subtypes or tumour localizations. After efficient therapy, the tumour image intensities and relaxation rates approached those of muscle and fibrous tissue, but remained at pre-therapy values when the patient was not in full remission. A similar pattern was found in a 'normal-tissue'--'tumour' plot, based on vector analysis of the original sets of 4 images. It is concluded that persistent tumour involvement in the mediastinum may be distinguished from fibrosis and that MRI may thus be of value in the follow-up of patients with Hodgkin's disease. |
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Authors:
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R Nyman; S Rehn; B Glimelius; H Hagberg; A Hemmingsson; B Jung |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta radiologica (Stockholm, Sweden : 1987) Volume: 28 ISSN: 0284-1851 ISO Abbreviation: Acta Radiol Publication Date: 1987 Mar-Apr |
Date Detail:
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Created Date: 1987-07-17 Completed Date: 1987-07-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8706123 Medline TA: Acta Radiol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 145-51 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Combined Modality Therapy Female Follow-Up Studies Hodgkin Disease / diagnosis*, drug therapy, radiotherapy Humans Magnetic Resonance Spectroscopy / diagnostic use* Male Mediastinal Neoplasms / diagnosis*, drug therapy, radiotherapy Middle Aged |
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