Document Detail


Magnetic resonance imaging assessment of fibrovascular ingrowth into porous polyethylene orbital implants.
MedLine Citation:
PMID:  16764656     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: To evaluate fibrovascular ingrowth into porous polyethylene orbital implants, using serial gadolinium (Gd)-enhanced magnetic resonance imaging (MRI). METHODS: 40 rabbits were divided into two groups, according to the surgical techniques used. Group 1 underwent enucleation of one eye and Medpor implantation, group 2 underwent evisceration and Medpor implantation. All subjects from each group were examined via MRI, and the implants were assessed histologically on the first, second, fourth and eighth postoperative weeks. The degree to which fibrovascular ingrowth occurred was then assessed by measuring the Gd-enhanced portion via MRI, as well as by histologic examination. RESULTS: There was a significant correlation between the enhanced area on MRI and the fibrovascularized area observed upon histological examination in the two study groups (group 1: r = 0.850 P < 0.001, group 2: r = 0.788, P < 0.001). The area enhanced on MRI was 2.70% smaller in mean value than the fibrovascularized area observed upon histological examination. There was no differences in fibrovascular ingrowth between group 1 and 2. It was also found that there was no differences between the two groups with regard to the enhanced areas on MRI. CONCLUSION: Gd-enhanced MRI study proved to be an excellent method for the assessment of fibrovascular ingrowth into the Medpor orbital implants, after both enucleation and evisceration.
Authors:
Hee Young Choi; Jong Soo Lee; Hyun Jun Park; Boo Sup Oum; Hak Jin Kim; Do Youn Park
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical & experimental ophthalmology     Volume:  34     ISSN:  1442-6404     ISO Abbreviation:  Clin. Experiment. Ophthalmol.     Publication Date:    2006 May-Jun
Date Detail:
Created Date:  2006-06-12     Completed Date:  2006-08-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100896531     Medline TA:  Clin Experiment Ophthalmol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  354-9     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, College of Medicine, Pusan National University, Busan, Korea. hychoi@pusan.ac.kr
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MeSH Terms
Descriptor/Qualifier:
Animals
Eye Enucleation
Fibroblasts / cytology*
Magnetic Resonance Imaging / methods*
Neovascularization, Physiologic / physiology*
Orbital Implants*
Polyethylenes*
Rabbits
Chemical
Reg. No./Substance:
0/Medpor; 0/Polyethylenes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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