Document Detail


Magnetic resonance cholangiography in the diagnosis of biliary complications after orthotopic liver transplantation.
MedLine Citation:
PMID:  15194328     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The aim of our study was to evaluate the role of magnetic resonance cholangiography (MRC) in the diagnosis of biliary tract complications (BC) after orthotopic liver transplantation (OLT). MATERIALS AND METHODS: Among 21 OLT patients who underwent routine follow-up MRC using a breath-hold T2-weighted turbo spin-echo sequence with half-Fourier acquisition (HASTE), 5 had an elevated serum alkaline phosphatase level. Diagnostic confirmation was obtained with endoscopic retrograde cholangiography (ERC) (n = 11), surgery (n = 3), or clinical and laboratory follow-up of at least 1 year (n = 8). RESULTS: In 13 patients, no abnormality of the biliary tract was detected using MRC. In 8 patients, anastomotic strictures were diagnosed, 7 of which were confirmed at surgery or using ERC. One patient with normal findings at MRC and abnormal liver function test results was found to have a stricture at ERC. All patients with normal MRC and liver function tests had 1 year of uneventful follow-up and were considered true-negative cases. We found that MRC had 87.5% sensitivity, 92.3% specificity, 87.5% positive predictive value, 92.3% negative predictive value, and 90.4% accuracy for the diagnosis of BC. CONCLUSION: MRC is a valuable examination to detect BC after OLT. It provides useful information for planning interventional procedures.
Authors:
M M Linhares; A M Gonzalez; S M Goldman; R D S Coelho; N Y Sato; R M A M Moura; M H G Silva; V P Lanzoni; A Salzedas; C B Serra; T Succi; G D'Ippolito; J Szejnfeld; T Triviño
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transplantation proceedings     Volume:  36     ISSN:  0041-1345     ISO Abbreviation:  Transplant. Proc.     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-06-14     Completed Date:  2005-04-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243532     Medline TA:  Transplant Proc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  947-8     Citation Subset:  IM    
Affiliation:
São Paulo Federal University Medical School, Federal University of São Paulo, Sao Paulo, Brazil. marbet@uol.com.br
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MeSH Terms
Descriptor/Qualifier:
Cholangiography*
Gallbladder Diseases / radiography*
Humans
Liver Transplantation / adverse effects*
Magnetic Resonance Angiography*
Postoperative Complications / radiography
Predictive Value of Tests
Reproducibility of Results
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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