Document Detail


Magnetic resonance brain imaging lacks sensitivity for AIDS associated cytomegalovirus encephalitis.
MedLine Citation:
PMID:  8972421     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Six patients are presented who died with active cytomegalovirus (CMV) encephalitis in whom brain MR scans within 25 days of death failed to reveal distinctive findings suggesting the diagnosis of CMV encephalitis. While MR scanning is crucial to evulation of AIDS patients developing neurologic complications, it is not sensitive to the presence of CMV encephalitis even when it is quite severe. The diagnosis of CMV encephalitis during life rests on characteristic clinical findings supported by a typical laboratory measures including the presence of CMV DNA in cerebrospinal fluid as detected by polymerase chain reaction.
Authors:
D B Clifford; J R Arribas; G A Storch; W Tourtellote; F J Wippold
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of neurovirology     Volume:  2     ISSN:  1355-0284     ISO Abbreviation:  J. Neurovirol.     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-03-17     Completed Date:  1997-03-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9508123     Medline TA:  J Neurovirol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  397-403     Citation Subset:  IM; X    
Affiliation:
Department of Neurology and Neurological Surgery (Neurology), Washington University School of Medicine, St Louis Missouri, USA.
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MeSH Terms
Descriptor/Qualifier:
AIDS-Related Opportunistic Infections / diagnosis*
Adult
Cytomegalovirus*
Cytomegalovirus Infections / diagnosis*
Encephalitis, Viral / diagnosis*
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Sensitivity and Specificity
Grant Support
ID/Acronym/Agency:
AI25903/AI/NIAID NIH HHS; NS32228/NS/NINDS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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