| Magnetic resonance angiography of the extracranial carotid system. | |
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MedLine Citation:
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PMID: 19512856 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To discuss the role of magnetic resonance angiography (MRA) in the evaluation of the extracranial carotid system with an emphasis on atherosclerosis and to briefly address the role of magnetic resonance imaging in imaging of carotid atherosclerotic plaque. METHODS: Literature and institutional review. DISCUSSION: The North American Symptomatic Carotid Endarterectomy Trial and European Carotid Surgery Trial studies have emphasized the importance of recognition and treatment of carotid stenosis in the prevention of ischemic stroke. Magnetic resonance angiography is a viable tool in the screening and quantification of this entity. Both time of flight and contrast-enhanced MRA techniques are available for clinical use, each with distinct advantages and limitations. A thorough understanding of these is vital for correct performance and interpretation of these studies. Plaque imaging with magnetic resonance imaging offers new insights into the pathophysiology of the atherosclerotic process and may be used in the future to monitor response to lipid-lowering drug therapy. CONCLUSION: Magnetic resonance angiography is a robust imaging technique for evaluation of the extracranial carotid circulation. The radiologist must be aware of the advantages and limitations of the different techniques available. Contrast-enhanced MRA is now the most widely performed technique. It can be used to replace digital subtraction angiography in the evaluation of carotid stenosis in most clinical settings. |
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Authors:
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Prashant Raghavan; Sugoto Mukherjee; John Gaughen; C Douglas Phillips |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Topics in magnetic resonance imaging : TMRI Volume: 19 ISSN: 1536-1004 ISO Abbreviation: Top Magn Reson Imaging Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2009-06-10 Completed Date: 2009-08-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8913523 Medline TA: Top Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 241-9 Citation Subset: IM |
Affiliation:
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Department of Neuroradiology, University of Virginia Health Systems, Charlottesville, VA 22908, USA. pr9k@virginia.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiography, Digital Subtraction Arteriosclerosis / diagnosis* Carotid Arteries / pathology Carotid Stenosis / diagnosis* Clinical Trials as Topic Contrast Media Humans Imaging, Three-Dimensional Magnetic Resonance Angiography / methods* Stroke / prevention & control |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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