| Magnetic pancreaticobiliary stents and retrieval system: obviating the need for repeat endoscopy (with ). | |
| | |
MedLine Citation:
|
PMID: 22226385 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND: Plastic stents are routinely placed in the pancreaticobiliary system to facilitate drainage. A second endoscopy is often required for stent removal. We have developed magnetic pancreaticobiliary stents that can be removed by using an external hand-held magnet, thereby obviating the need for a second endoscopy. OBJECTIVE: To develop and test magnetic pancreaticobiliary stents and retrieval system in ex-vivo and in-vivo porcine models. SETTING: Animal laboratory. DESIGN: Benchtop and animal study. ANIMALS: 5 pigs. INTERVENTIONS: Design: Computer simulations determined both the optimal design of cylindrical magnets attached to the distal aspect of existing plastic stents and the optimal design of the external hand-held magnet. Benchtop ex-vivo experiments measured magnetic force to validate the design. In-vivo analysis: In 5 Yorkshire pigs, magnetic stents were deployed into the common bile duct by using a conventional duodenoscope. An external hand-held magnet was applied for stent removal. Stent insertion and removal times were recorded. MAIN OUTCOME MEASUREMENTS: Technical feasibility. RESULTS: Magnetic stents of varying lengths and calibers were successfully created. In ex-vivo testing, the capture distance was 10.0 cm. During in-vivo testing, the magnetic stents were inserted and removed easily. The mean insertion and removal times were 3.2 minutes and 33 seconds, respectively. LIMITATIONS: Animal study, small numbers. CONCLUSIONS: Magnetic pancreaticobiliary stents and associated retrieval system were successfully designed and tested in the acute porcine model. An external, noninvasive means of stent removal potentially obviates the need for a second endoscopy, which could represent a major gain both for patients and in health care savings. |
| | |
Authors:
|
Marvin Ryou; Padraig Cantillon-Murphy; Sohail N Shaikh; Dan Azagury; Michele B Ryan; Jeffrey H Lang; Christopher C Thompson |
Related Documents
:
|
8891235 - Three-dimensional brain visualization for metachromatic leukodystrophy. 19952905 - Traumatic disruption of the optic chiasm. 11163415 - Oriented sectioning of irregular tissue blocks in relation to computerized scanning mod... 20202775 - Parenchymal lymphoma of the brain on initial mr imaging: a comparative study between pr... 21475005 - Positron emission tomography/computed tomographic scans compared to computed tomographi... 18574805 - Chemical design of nanoparticle probes for high-performance magnetic resonance imaging. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-5 |
Journal Detail:
|
Title: Gastrointestinal endoscopy Volume: - ISSN: 1097-6779 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-9 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0010505 Medline TA: Gastrointest Endosc Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved. |
Affiliation:
|
Division of Gastroenterology, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A new method in the diagnosis of reflux esophagitis: confocal endomicroscopy.
Next Document: Perspectives on the New Kidney Disease Education Benefit: Early Awareness, Race and Kidney Transplan...