Document Detail


Magnetic nanoparticles in biomedicine: synthesis, functionalization and applications.
MedLine Citation:
PMID:  21128722     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Magnetic nanoparticles continue to garner widespread interest in biomedical applications, such as visualization agents in MRI, therapeutic vehicles for drug delivery and heat mediators in hyperthermia. Recent advances in colloidal synthesis and surface-functionalization techniques have greatly contributed to the design of functionalized magnetic nanoparticles with controlled properties and multifunctional capabilities, which are harnessed for dual diagnostic and therapeutic purposes. The surface-functionalization methods in particular have aided in obtaining magnetic nanoparticles coated with molecules, with tailored functionalities that enhance their applications. In this article, the methods of synthesis and functionalization are examined, with emphasis on how these impact their biomedical applications.
Authors:
Reynolds A Frimpong; J Zach Hilt
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nanomedicine (London, England)     Volume:  5     ISSN:  1748-6963     ISO Abbreviation:  Nanomedicine (Lond)     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-12-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101278111     Medline TA:  Nanomedicine (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  1401-14     Citation Subset:  IM    
Affiliation:
Department of Chemical & Materials Engineering, University of Kentucky, Lexington, KY 40506, USA.
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