Document Detail


Magnetic fields abolish the enhanced nocturnal analgesic response to morphine in mice.
MedLine Citation:
PMID:  6538981     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mice given morphine displayed diel rhythms in the latency of their behavioral response to placement on a hot plate, there being a several fold increase in their nocturnal reaction times. Exposure to a rotating magnetic field eliminated the day-night analgesia rhythms, reducing over 5-10 days the enhanced nocturnal latencies to those found during the day. The attenuation returned to normal nocturnal levels several days after removal of the rotating magnetic field and could be subsequently re-established by reapplication of the magnetic field condition. It is suggested that these changes in analgesia may reflect alterations in the activity of the pineal gland during exposure to magnetic fields.
Authors:
M Kavaliers; K P Ossenkopp; M Hirst
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Physiology & behavior     Volume:  32     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1984 Feb 
Date Detail:
Created Date:  1984-06-19     Completed Date:  1984-06-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  261-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Analgesia*
Animals
Circadian Rhythm*
Hot Temperature
Magnetics*
Male
Mice
Mice, Inbred Strains
Morphine / pharmacology*
Pineal Gland / physiology
Reaction Time
Chemical
Reg. No./Substance:
57-27-2/Morphine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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