Document Detail


Magnetic field switching of nanoparticles between orthogonal microfluidic channels.
MedLine Citation:
PMID:  17585838     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
This paper reports on the manipulation of magnetic nanoparticles between microfluidic channels by the application of an external magnet. Two orthogonal channels were prepared using standard PDMS techniques with pressure-driven flow used to deliver the mobile phase. To study the ability to control magnetic nanoparticles within micrometer-sized channels, Fe2O3, MnFe2O4, and Au nanoparticle samples were compared. For the magnetic particles, transfer between flow streams is greatly increased by placing a permanent magnet beneath the intersection of the channels, but no change is observed for the nonmagnetic Au particles. More nanoparticles are magnetically transferred into the orthogonal channel as the solvent flow rate decreases. We demonstrate the ability to use this technique to perform multiple injections of plugs of magnetic particles by periodic application of a magnetic field.
Authors:
Andrew H Latham; Anand N Tarpara; Mary Elizabeth Williams
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Publication Detail:
Type:  Journal Article     Date:  2007-06-23
Journal Detail:
Title:  Analytical chemistry     Volume:  79     ISSN:  0003-2700     ISO Abbreviation:  Anal. Chem.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-07-31     Completed Date:  2007-10-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370536     Medline TA:  Anal Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5746-52     Citation Subset:  -    
Affiliation:
Department of Chemistry, The Pennsylvania State University, 104 Chemistry Building, University Park, Pennsylvania 16802, USA.
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