| Magnetic field homogenization of the human prefrontal cortex with a set of localized electrical coils. | |
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MedLine Citation:
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PMID: 19918909 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The prefrontal cortex is a common target brain structure in psychiatry and neuroscience due to its role in working memory and cognitive control. Large differences in magnetic susceptibility between the air-filled sinuses and the tissue/bone in the frontal part of the human head cause a strong and highly localized magnetic field focus in the prefrontal cortex. As a result, image distortion and signal dropout are observed in MR imaging. A set of external electrical coils is presented that provides localized and high-amplitude shim fields in the prefrontal cortex, with minimum impact on the rest of the brain when combined with regular zero- to second-order spherical harmonics shimming. The experimental realization of the new shim method strongly minimized or even eliminated signal dropout in gradient-echo images acquired at settings typically used in functional magnetic resonance at 4 T. |
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Authors:
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Christoph Juchem; Terence W Nixon; Scott McIntyre; Douglas L Rothman; Robin A de Graaf |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: 63 ISSN: 1522-2594 ISO Abbreviation: Magn Reson Med Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-28 Completed Date: 2010-03-10 Revised Date: 2011-09-26 |
Medline Journal Info:
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Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: United States |
Other Details:
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Languages: eng Pagination: 171-80 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2009 Wiley-Liss, Inc. |
Affiliation:
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Yale University School of Medicine, Department of Diagnostic Radiology, Magnetic Resonance Research Center, New Haven, Connecticut 06520, USA. christoph.juchem@yale.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Computer-Aided Design Equipment Design Equipment Failure Analysis Humans Image Enhancement / instrumentation* Image Interpretation, Computer-Assisted / instrumentation* Magnetic Resonance Imaging / instrumentation* Magnetics / instrumentation* Prefrontal Cortex / anatomy & histology* Reproducibility of Results Sensitivity and Specificity Transducers* |
| Grant Support | |
ID/Acronym/Agency:
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R01 EB000473-09/EB/NIBIB NIH HHS; R01-EB000473/EB/NIBIB NIH HHS; R21 CA118503-02/CA/NCI NIH HHS; R21/R33-CA118503/CA/NCI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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