Document Detail


Magnetic resonance angiography findings in patients with ischemic stroke from North India.
MedLine Citation:
PMID:  20189091     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: We sought to evaluate the magnetic resonance (MR) angiography (MRA) findings in patients with ischemic stroke (IS) from North India and correlate the changes with various conventional and nonconventional risk factors. METHODS: The study took place at a tertiary care teaching hospital. The patients with IS were clinically evaluated including body mass index, dietary habits, and family history of stroke. MR imaging, MRA, and testing for blood sugar, lipid profile, B12, folic acid, and homocysteine were carried out. The MRA abnormalities were considered significant if stenosis was 50% or greater and these were categorized into extracranial (EC), intracranial (IC), or combined lesions. The location of infarct on MR imaging was also noted. RESULTS: There were 151 patients whose median age was 60 (22-85) years. The EC MRA was abnormal in 56.3% and the IC MRA in 63.3% of patients, the internal carotid artery being the most common site. Corresponding infarct was present in 64.7% and noncorresponding in 45.3% of patients. The MRA abnormality positively correlated with hypertension and diabetes, and negatively with alcohol consumption. The EC MRA abnormality was more common in upper caste Hindus and Muslims and in the city dwellers. CONCLUSION: In North Indian patients with IS, the frequency of EC and IC MRA abnormality lies between Whites and the Orientals.
Authors:
Gyanendra Kumar; Jayantee Kalita; Bishwanath Kumar; Vikas Bansal; Sunil K Jain; UshaKant Misra
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association     Volume:  19     ISSN:  1532-8511     ISO Abbreviation:  J Stroke Cerebrovasc Dis     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-01     Completed Date:  2010-06-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111633     Medline TA:  J Stroke Cerebrovasc Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  146-52     Citation Subset:  IM    
Copyright Information:
Copyright 2010 National Stroke Association. Published by Elsevier Inc. All rights reserved.
Affiliation:
Department of Neurology, University of Missouri-Health Care Columbia, Columbia, MO, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Alcohol Drinking / epidemiology
Biological Markers / analysis,  blood
Blood Glucose / physiology
Body Mass Index
Brain Ischemia / epidemiology,  pathology*,  physiopathology
Carotid Artery, External / pathology*,  physiopathology
Carotid Artery, Internal / pathology*,  physiopathology
Continental Population Groups
Diabetes Mellitus / epidemiology
Female
Folic Acid / analysis,  blood
Food Habits
Homocysteine / analysis,  blood
Humans
Hypertension / epidemiology
India / epidemiology
Lipids / analysis,  blood
Magnetic Resonance Angiography
Male
Middle Aged
Risk Factors
Socioeconomic Factors
Stroke / epidemiology,  pathology*,  physiopathology
Vitamin B 12 / analysis,  blood
Young Adult
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Blood Glucose; 0/Lipids; 454-28-4/Homocysteine; 59-30-3/Folic Acid; 68-19-9/Vitamin B 12

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