Document Detail


Magnaporthe oryzae MTP1 gene encodes a type III transmembrane protein involved in conidiation and conidial germination.
MedLine Citation:
PMID:  18600780     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study the MTP1 gene, encoding a type III integral transmembrane protein, was isolated from the rice blast fungus Magnaporthe oryzae. The Mtp1 protein is 520 amino acids long and is comparable to the Ytp1 protein of Saccharomyces cerevisiae with 46% sequence similarity. Prediction programs and MTP1-GFP (green fluorescent protein) fusion expression results indicate that Mtp1 is a protein located at several membranes in the cytoplasm. The functions of the MTP1 gene in the growth and development of the fungus were studied using an MTP1 gene knockout mutant. The MTP1 gene was primarily expressed at the hyphal and conidial stages and is necessary for conidiation and conidial germination, but is not required for pathogenicity. The Deltamtp1 mutant grew more efficiently than the wild type strain on non-fermentable carbon sources, implying that the MTP1 gene has a unique role in respiratory growth and carbon source use.
Authors:
Qin Lu; Jian-Ping Lu; Xiao-Dong Li; Xiao-Hong Liu; Hang Min; Fu-Cheng Lin
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of Zhejiang University. Science. B     Volume:  9     ISSN:  1673-1581     ISO Abbreviation:  J Zhejiang Univ Sci B     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-07-07     Completed Date:  2008-08-12     Revised Date:  2013-06-05    
Medline Journal Info:
Nlm Unique ID:  101236535     Medline TA:  J Zhejiang Univ Sci B     Country:  China    
Other Details:
Languages:  eng     Pagination:  511-9     Citation Subset:  IM    
Affiliation:
College of Life Sciences, Zhejiang University, Hangzhou, China.
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MeSH Terms
Descriptor/Qualifier:
Fungal Proteins / genetics*,  physiology
Genes, Fungal
Magnaporthe / genetics*
Membrane Proteins / genetics*
Oryza sativa / microbiology
Promoter Regions, Genetic
Chemical
Reg. No./Substance:
0/Fungal Proteins; 0/Membrane Proteins
Comments/Corrections

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