Document Detail

Magic syndrome and true aortic aneurysm.
MedLine Citation:
PMID:  17657547     Owner:  NLM     Status:  MEDLINE    
Magic syndrome is a very uncommon disease, and vascular involvement is exceptional; only one case has been reported in the literature associated to a true aortic aneurysm. The treatment of aneurysms recommended in these patients is based on isolated cases and includes corticosteroids, other immunosuppressant drugs, and surgery. We report a case of a patient with Magic syndrome who developed aneurysm at the end of the aorta during treatment with infliximab, corticosteroids, and cyclosporine and who needed endovascular prosthesis implantation. After 12 months, she suffered an aneurysm of the ascending aorta, dilatation of the sinotubular junction, and severe aortic insufficiency, which forced surgery. During this time, the patient finally died.
C Hidalgo-Tenorio; J M Sabio-Sánchez; P J P Linares; L M Salmerón; E Ros-Die; J Jiménez-Alonso
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-07-27
Journal Detail:
Title:  Clinical rheumatology     Volume:  27     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-11-23     Completed Date:  2008-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  115-7     Citation Subset:  IM    
Autoimmune Disease Unit, Internal Medicine Service, University Hospital Virgen de las Nieves, Granada, Spain.
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MeSH Terms
Aortic Aneurysm / complications*,  pathology,  surgery
Behcet Syndrome / complications*,  pathology,  therapy
Cyclophosphamide / therapeutic use
Drug Therapy, Combination
Fatal Outcome
Glucocorticoids / therapeutic use
Immunosuppressive Agents / therapeutic use
Methylprednisolone / therapeutic use
Polychondritis, Relapsing / complications*,  pathology,  therapy
Prednisone / therapeutic use
Reg. No./Substance:
0/Glucocorticoids; 0/Immunosuppressive Agents; 50-18-0/Cyclophosphamide; 53-03-2/Prednisone; 83-43-2/Methylprednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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