Document Detail

Macular pigment: influences on visual acuity and visibility.
MedLine Citation:
PMID:  12062535     Owner:  NLM     Status:  MEDLINE    
There is increasing evidence that the macular pigment (MP) carotenoids lutein (L) and zeaxanthin (Z) protect the retina and lens from age-related loss. As a result, the use of L and Z supplements has increased dramatically in recent years. An increasing number of reports have suggested that L and Z supplementation (and increased MP density) are related to improved visual performance in normal subjects and patients with retinal and lenticular disease. These improvements in vision could be due either to changes in the underlying biology and/or optical changes. The optical mechanisms, i.e., preferential absorption of short-wave light, underlying these putative improvements in vision, however, have not been properly evaluated. Two major hypotheses are discussed. The acuity hypothesis posits that MP could improve visual function by reducing the effects of chromatic aberration. The visibility hypothesis is based on the idea that MP may improve vision through the atmosphere by preferentially absorbing blue haze (short-wave dominant air light that produces a veiling luminance when viewing objects at a distance).
Billy R Wooten; Billy R Hammond
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Progress in retinal and eye research     Volume:  21     ISSN:  1350-9462     ISO Abbreviation:  Prog Retin Eye Res     Publication Date:  2002 Mar 
Date Detail:
Created Date:  2002-06-13     Completed Date:  2002-11-13     Revised Date:  2009-01-15    
Medline Journal Info:
Nlm Unique ID:  9431859     Medline TA:  Prog Retin Eye Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  225-40     Citation Subset:  IM    
Walter S. Hunter Laboratory, Brown University, Box 1853, Providence, RI 02912, USA.
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MeSH Terms
Macula Lutea / metabolism*
Models, Biological
Retinal Pigments / metabolism*
Vision, Ocular / physiology*
Visual Acuity* / physiology*
Reg. No./Substance:
0/Retinal Pigments

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