| Macular lesion resembling adult-onset vitelliform macular dystrophy in Kearns-Sayre syndrome with multiple mtDNA deletions. | |
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MedLine Citation:
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PMID: 20497429 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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We present the case of a 48-year-old woman with a clinically and histopathologically confirmed Kearns-Sayre syndrome who developed a maculopathy resembling an adult-onset vitelliform macular dystrophy in her right eye. DNA analysis identified the presence of multiple deletions in the mtDNA of the muscle sample, with the common deletion of 4977 bp the most abundant. To the best of our knowledge, there have been no previous reports of such macular lesion occurring in association with Kearns-Sayre syndrome. |
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Authors:
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Francisco J Ascaso; Ester Lopez-Gallardo; Eduardo Del Prado; Eduardo Ruiz-Pesini; Julio Montoya |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical & experimental ophthalmology Volume: 38 ISSN: 1442-9071 ISO Abbreviation: Clin. Experiment. Ophthalmol. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100896531 Medline TA: Clin Experiment Ophthalmol Country: Australia |
Other Details:
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Languages: eng Pagination: 812-6 Citation Subset: IM |
Copyright Information:
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© 2010 The Authors. Clinical and Experimental Ophthalmology © 2010 Royal Australian and New Zealand College of Ophthalmologists. |
Affiliation:
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Department of Ophthalmology, 'Lozano Blesa' University Clinic Hospital, Zaragoza, Spain. jascaso@gmail.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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