Document Detail

Macular edema and visual loss after macular pucker surgery with ICG-assisted internal limiting membrane peeling.
MedLine Citation:
PMID:  15812777     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To describe the occurrence of massive macular edema and visual loss after indocyanine green-assisted (ICG) macular pucker surgery. METHODS/RESULTS: A 74 years old female presented with a macular pucker and a hypertrophy of the retinal pigment epithelium (RPE) in her left eye. The preoperative visual acuity (VA) was 20/100. Surgery consisted of cataract extraction, lens implantation and standard pars plana vitrectomy with peeling of epiretinal tissue followed by the removal of the internal limiting membrane (ILM) remnants stained using a 0.05% ICG solution. One day after surgery, VA was counting fingers. There was an extensive macular edema and retinal thickening with hyperfluorescence during fluorescein angiography and pronounced autofluorescence using ICG filters. During follow up, the macular edema resolved completely, but VA decreased to 20/800 at six months postoperatively. There was a central scotoma and unstable fixation seen during microperimetry. DISCUSSION: This case report indicates that ICG might come into contact with bare retina if injected following removal of epiretinal membranes. Whether the observed RPE hypertrophy might have contributed to the pathogenesis of the adverse effect described remains hypothetical.
D Tognetto; C Haritoglou; A Kampik; G Ravalico
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  15     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    2005 Mar-Apr
Date Detail:
Created Date:  2005-04-06     Completed Date:  2005-06-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  289-91     Citation Subset:  IM    
Clinica Oculistica Università di Trieste, Ospedale Maggiore--Italy.
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MeSH Terms
Basement Membrane / surgery
Blindness / etiology*
Cataract Extraction
Coloring Agents / diagnostic use*
Epiretinal Membrane / surgery*
Fluorescein Angiography
Indocyanine Green / diagnostic use*
Lens Implantation, Intraocular
Macular Edema / etiology*
Postoperative Complications*
Staining and Labeling / methods
Visual Acuity
Reg. No./Substance:
0/Coloring Agents; 3599-32-4/Indocyanine Green

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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