Document Detail

Macroscopic two-pump two-vasculature cardiovascular model to support treatment of acute heart failure.
MedLine Citation:
PMID:  19965188     Owner:  NLM     Status:  MEDLINE    
Comprehensive understanding of hemodynamics remains a challenge even for expert cardiologists, partially due to a lack of an appropriate macroscopic model. We attempted to amend three major problems of Guyton's conceptual model (unknown left atrial pressure, unilateral heart damage, blood redistribution) and developed a comprehensive macroscopic model of hemodynamics that provides quantitative information. We incorporated a third axis of left atrial pressure, resulting in a 3D coordinate system. Pump functions of left and right heart are expressed by an integrated cardiac output curve, and the capacitive function of total vasculature by a venous return surface. The equations for both the cardiac output curve and venous return surface would facilitate precise diagnosis (especially evaluation of blood volume) and choice of appropriate treatments, including application to autopilot systems.
Masaru Sugimachi; Kenji Sunagawa; Kazunori Uemura; Atsunori Kamiya; Shuji Shimizu; Masashi Inagaki; Toshiaki Shishido
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2009     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-07     Completed Date:  2010-03-16     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2365-8     Citation Subset:  IM    
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MeSH Terms
Blood Pressure
Blood Volume
Cardiac Output
Computational Biology / methods
Computer Simulation
Heart Atria / pathology
Heart Failure / diagnosis*,  physiopathology*
Linear Models
Models, Cardiovascular
Reproducibility of Results

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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