Document Detail


Macrophage inhibitor factor (MIF) in cutaneous lymphoproliferative diseases.
MedLine Citation:
PMID:  136265     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Macrophage migration inhibitor factor (MIF) activity in the sera of patients with mycosis fungoides, Sézary syndrome, and cutaneous lymphoma was observed in the sera of eight of the ten patients with stage II (infiltrative) mycosis fungoides, but in only one of the eight patients with stage I and in neither of the two patients with stage III mycosis fungoides. Two of the three patients with Sézary syndrome had MIF in the serum. No MIF was observed in cutaneous lymphoma. These data support the concept that Sézary syndrome and mycosis fungoides are T-cell diseases, and transitional, prelymphomatous diseases.
Authors:
P Umbert; R W Belcher; R K Winkelmann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of dermatology     Volume:  95     ISSN:  0007-0963     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  1976 Nov 
Date Detail:
Created Date:  1977-01-29     Completed Date:  1977-01-29     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  475-80     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cell Migration Inhibition
Dermatitis, Exfoliative / immunology
Humans
Hypersensitivity, Delayed
Keratoderma, Palmoplantar / immunology
Lymphatic Diseases / immunology
Lymphoma / immunology
Macrophage Migration-Inhibitory Factors / blood*
Macrophages / immunology*
Mycosis Fungoides / immunology
Skin Diseases / immunology*
Skin Neoplasms / immunology
Skin Tests
Syndrome
T-Lymphocytes
Chemical
Reg. No./Substance:
0/Macrophage Migration-Inhibitory Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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