Document Detail


Macadamia nut consumption lowers plasma total and LDL cholesterol levels in hypercholesterolemic men.
MedLine Citation:
PMID:  12672919     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study was conducted to assess the cholesterol-lowering potential of macadamia nuts. Seventeen hypercholesterolemic men (mean age 54 y) were given macadamia nuts (40-90 g/d), equivalent to 15% energy intake, for 4 wk. Plasma total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides and homocysteine concentrations and the fatty acid composition of plasma lipids were determined before and after treatment. Plasma MUFA 16:1(n-7), 18:1(n-7) and 20:1(n-9) were elevated after intervention with macadamia nuts. Plasma (n-6) and (n-3) PUFA concentrations were unaffected by macadamia nut consumption. Plasma total cholesterol and LDL cholesterol concentrations decreased by 3.0 and 5.3%, respectively, and HDL cholesterol levels increased by 7.9% in hypercholesterolemic men after macadamia nut consumption. Plasma triglyceride and homocysteine concentrations were not affected by treatment. Macadamia nut consumption was associated with a significant increase in the relative intake of MUFA and a reduced relative intake of saturated fatty acids and PUFA. This study demonstrates that macadamia nut consumption as part of a healthy diet favorably modifies the plasma lipid profile in hypercholesterolemic men despite their diet being high in fat.
Authors:
Manohar L Garg; Robert J Blake; Ron B H Wills
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of nutrition     Volume:  133     ISSN:  0022-3166     ISO Abbreviation:  J. Nutr.     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-04-03     Completed Date:  2003-04-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1060-3     Citation Subset:  IM    
Affiliation:
Nutrition & Dietetics, School of Health Sciences, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia. manohar.garg@newcastle.edu.au
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MeSH Terms
Descriptor/Qualifier:
Cholesterol / blood*
Cholesterol, LDL / blood*
Homocysteine / blood
Humans
Hypercholesterolemia / blood*
Male
Middle Aged
Nuts*
Chemical
Reg. No./Substance:
0/Cholesterol, LDL; 454-28-4/Homocysteine; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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